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Why I Believe in Natural Acclimatisation Over Diamox

Posted: Wednesday February 19, 2025

Having spent years exploring high-altitude environments, I’ve experienced firsthand the challenges of adjusting to reduced oxygen levels.  I’ve experienced altitude sickness (AMS), tried Diamox, and learned the hard way that no pill can replace the simple but crucial process of proper acclimatisation.  Yet, more than ever, I see Diamox being touted on social media as a magic bullet, something that guarantees a safe ascent.  This is a dangerous misconception.

My Experience with Altitude

Not every high-altitude trip has gone smoothly for me.  When I first started going to altitude, I was hit hard with AMS and couldn’t understand why.  I was fit and strong.  How come I couldn’t acclimatize?  I’ve taken Diamox to help me acclimatise.  On one occasion, I took Diamox as a precaution, hoping it would help.  While it did lessen my symptoms, I still had to slow down, rest, and let my body adjust.  I’ve been on trips where I didn’t really do anything and didn’t take any drugs and adapted well.  These experiences helped me to learn how to set the conditions for good natural acclimatisation and cemented what I now firmly believe: the most effective way to prevent altitude sickness is a slow, steady ascent, not a pill.

 

What is Diamox and How Does it Work?

Diamox (acetazolamide) is a medication that can speed up acclimatisation by altering the body’s acid-base balance.  It works by making the blood more acidic, which stimulates breathing and increases oxygen intake.  This mimics the natural adaptation process, helping the body adjust to altitude more quickly.

The Wilderness Medical Society acknowledges that Diamox can be useful for AMS prevention, especially when a slow ascent isn’t possible or for those with a history of altitude illness.  However, it’s not a cure-all and should never replace proper acclimatisation.

 

Pros and Cons of Using Diamox

Pros:

✔      Diamox Speeds up Acclimatisation.  It can help the body adjust faster, reducing AMS symptoms.

✔      Diamox can be useful for Rapid Ascents.  If time constraints prevent a gradual ascent, Diamox may help mitigate some effects.

✔      Diamox can be Beneficial for Those Prone to AMS.  If someone has a history of altitude sickness, Diamox may lower their risk of getting AMS.

Cons:

✖      Diamox has Side Effects.  Common issues include tingling fingers, frequent urination, nausea, and taste changes.  These can be uncomfortable when you’re already dealing with altitude’s challenges.

✖      Diamox can give you a False Confidence.  Some people assume taking Diamox makes them immune to AMS, leading them to ascend too quickly, which can be dangerous.

✖      Diamox Doesn’t Replace Proper Acclimatisation.  While it can assist the process, it’s no substitute for taking your time and listening to your body.

 

The Best Way to Acclimatise

From my experience, what I’ve seen in others and learned along the way, the most reliable way to acclimatise is simple:

  1. Take Your Time. Increase your sleeping altitude gradually.  Ideally, no more than 500m of ascent per day above 3,000m, with acclimatisation days built in.

 

  1. Stay Hydrated. Dehydration worsens AMS symptoms, so drinking enough water is crucial.

 

  1. Eat Well. A diet rich in carbohydrates provides the necessary fuel for your body to adjust.

 

  1. Listen to Your Body. If you feel unwell, stop and give yourself time to adapt.  If symptoms get worse, descend.

 

  1. Follow the Climb High, Sleep Low Principle. This means ascending to a higher altitude during the day but returning to a lower elevation to sleep.  This helps the body adjust more effectively.

 

  1. Incorporate Acclimatisation Days. Even if you’re feeling fine, plan for acclimatisation days during your ascent.  These days allow your body to adapt without the added strain of continuous climbing.

 

  1. Avoid Alcohol and Sedatives. These can depress respiration and make acclimatisation more difficult.

 

  1. Consider Natural Supplements. Although not something I do personally, some people swear by ginger, ginkgo biloba, or other natural remedies, though scientific support varies.

 

The Psychological Aspect of Acclimatisation

One aspect often overlooked is the psychological challenge of altitude.  When AMS symptoms hit, they can be disorienting and even anxiety-inducing.  It’s easy to panic when you feel short of breath or develop a pounding headache.  The temptation to rely on a pill is strong, but trust in your body’s ability to adapt is crucial.

Learning to stay calm, pace yourself, and manage expectations can make a huge difference.  Anxiety can exacerbate symptoms, so mental preparation is just as important as physical conditioning.  Being honest about how you are feeling, practicing mindfulness, focusing on slow, controlled breathing, and having confidence in your acclimatisation strategy can help you push through the discomfort in a healthy, sustainable way.

When Diamox Might Be Necessary

I’m not completely against Diamox.  There are scenarios where it makes sense to use it.  If you have a pre-existing condition that makes acclimatisation harder, or if you’re forced to ascend quickly due to logistical reasons, taking Diamox may be a practical choice.  However, it should never be used as an excuse to push beyond your body’s limits.

If you choose to use Diamox, it’s essential to start taking it before you reach high altitude to gauge any side effects.  Consulting a doctor familiar with high-altitude travel is also crucial to determine the appropriate dosage and usage.

 

Final Thoughts

I understand why some people turn to Diamox, and in certain situations, it has its place.  But over the years, I’ve learned that there’s no shortcut to acclimatisation.  A slow, steady approach, combined with awareness of your body’s signals, is the safest and most effective way to acclimatise.

Climbing at altitude is as much about patience and respect for the mountain environment as it is about physical fitness and endurance.  Trust the process, take your time, and you’ll give yourself the best chance of success.  Natural acclimatisation not only strengthens your body’s ability to adapt but also deepens your connection to the mountains, something that no pill can replicate.

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